The Relationship Between Indestructible Healthy Lifestyle Patterns, Levels of Sensation-Seeking and Perceived Stress with Cognitive Performance in Older Adults with Hypertension

Document Type : Original Article

Author

Dept. of Psychology, Faculty of Human Sciences, University of Maragheh, Maragheh, Iran

Abstract

Abstract
Hypertension and cognitive impairments are common conditions among older adults. This study aimed to investigate the relationship between the Indivisible Self Model of Wellness (IS-WEL), sensation-seeking levels, and perceived stress with cognitive performance in older adults with hypertension. This was a descriptive-correlational study. The study population included all older adults diagnosed with hypertension in Urmia, Iran, in 2023. A total of 215 older adults with hypertension were selected from healthcare centers in Urmia through convenience sampling. Data were collected using Nasreddine et al.’s Montreal Cognitive Assessment, Myers et al.’s Wellness Evaluation of Lifestyle, Zuckerman’s Sensation Seeking Scale, and Cohen’s Perceived Stress Scale. Data were analyzed using Pearson’s correlation coefficient and multiple regression analysis in SPSS version 22. The results showed significant relationships between cognitive performance and IS-WEL, sensation-seeking, and perceived stress. The predictor variables explained 33% of the variance in cognitive performance (p<.001). Executive functioning accounted for 15%, excitement for 11%, self-socialization for 3%, self-coping for 2%, and perceived stress for 2% of the variance (p<.001). These findings suggest that older adults with hypertension tend to have weak IS-WEL, and high levels of sensation-seeking and perceived stress. Emotional regulation and stress management training are recommended to improve cognitive performance in this population.
EXTENDED ABSTRACT
 Introduction
Studies have shown that with the onset of aging, blood pressure tends to increase while cognitive performance declines. In the research literature, various factors have been investigated in relation to cognitive performance among older adults with hypertension, with the Indivisible Self Model of Wellness (IS-WEL) emerging as one of the most significant predictors. IS-WEL is a holistic model of wellness that conceptualizes health as the integrated functioning of multiple life domains, including physical, emotional, social, and spiritual aspects. As individuals grow older and enter later stages of life, the relevance of IS-WEL becomes increasingly pronounced. Another important factor associated with cognitive functioning in older adults is sensation-seeking. Sensation-seeking is rooted in an individual's arousal capacity; those with high levels of sensation-seeking tend to prefer constant mental stimulation, experience boredom with repetitive tasks, and seek out novel and stimulating experiences to maintain arousal. In addition, perceived stress is a psychological factor that can negatively impact cognitive performance, health, and well-being in older adults. Despite the importance of stress, emotional regulation, and healthy lifestyle patterns in this population, these variables have received relatively limited attention in the context of hypertension-related cognitive decline. Accordingly, the present study aimed to examine the relationship of IS-WEL, sensation-seeking, and perceived stress with cognitive performance in older adults with hypertension.
Method
The present study was fundamental in its objective and descriptive in its methodology. The statistical population consisted of older adults with hypertension residing in Urmia, Iran. A total of 215 individuals (112 men and 103 women) were selected through visits to healthcare centers in Urmia using a convenience sampling method. Initial coordination was made by visiting relevant health centers in Urmia and obtaining permission from their administrators, including the Hamrah Elderly Day Center. In an introductory session, the researcher introduced themselves, explained the study’s purpose to the participants, and provided full instructions on how to complete the questionnaires to ensure honest and voluntary participation. Eligible participants were selected based on inclusion criteria, and efforts were made to establish trust and ensure sincere responses from the sample group. Inclusion criteria were: (1) age between 65 and 85 years, and (2) literacy. Exclusion criteria included: (1) the presence of physical illnesses or psychiatric disorders, (2) use of psychiatric medications within the past year, and (3) unwillingness to participate in the study. Data collection instruments included Nasreddine et al.’s Montreal Cognitive Assessment, Myers et al.’s Wellness Evaluation of Lifestyle, Zuckerman’s Sensation Seeking Scale, and Cohen’s Perceived Stress Scale. On average, each participant required approximately 40 to 60 minutes to complete the questionnaires. The questionnaires were distributed among participants, and instructions were provided to ensure accurate completion. Participants were informed about the anonymity and confidentiality of their responses, and written informed consent was obtained prior to participation. Incomplete or invalid questionnaires were excluded from the final analysis. Following data collection, responses were entered into SPSS version 22 for statistical analysis. Pearson’s correlation coefficient, and multiple regression analysis were employed to analyze the data.
Results
Prior to conducting data analysis, the distribution of scores for all variables was assessed and found to be normal, and the assumptions of multicollinearity were satisfied. The independence of errors was evaluated using the Durbin-Watson statistic, with a coefficient of 1.91 indicating no autocorrelation. Following confirmation of the necessary assumptions, the study’s conceptual model was tested using stepwise multiple regression to predict cognitive performance based on sensation-seeking, perceived stress, and self-destructive healthy lifestyle patterns. The results of the regression analysis are presented in Table 1. Based on the results presented in Table 1, the predictor variables collectively explained 33% of the variance in cognitive performance (R²=.33). Specifically, executive functioning accounted for 15%, excitement for 11%, self-socialization for 3%, self-coping for 2%, and perceived stress for 2% of the variance.
The F-statistic for the overall regression model was significant at the .001 level, indicating that the combination of these five variables significantly predicts cognitive performance.
Conclusion
The association between healthy lifestyle patterns and cognitive performance in older adults with hypertension highlights the importance of promoting health-enhancing behaviors and ensuring optimal blood pressure control. Such efforts can contribute to an improved quality of life and a reduction in the burden of cognitive disorders among older adults. There exists a complex relationship between sensation-seeking tendencies and cognitive performance in older adults, particularly those with hypertension. Some studies have suggested that moderate levels of sensation-seeking may support the maintenance of cognitive functioning in this population. Individuals with moderate sensation-seeking tendencies are more likely to engage in cognitively and physically stimulating activities, which, in turn, may help preserve or even enhance cognitive abilities. In contrast, elevated levels of perceived stress have been shown to negatively influence cognitive functioning. Among older adults with hypertension, higher stress levels may disrupt daily routines, reduce adherence to healthy behaviors, and ultimately impair cognitive performance. Unhealthy lifestyle patterns can exacerbate both stress and hypertension, thereby compounding their detrimental effects on cognition. Conversely, adherence to a healthy lifestyle, characterized by regular physical activity, proper nutrition, stress management, and adequate social engagement, can enhance cognitive function and mitigate the adverse effects of both hypertension and psychological stress in older individuals. These findings emphasize the need for integrated health interventions targeting lifestyle modification in hypertensive older adults to protect and sustain cognitive health.
Ethical Consideration
Ethics Code
 This study was approved by the Ethics Committee of Maragheh University with the ethics code 015 IR.UM.1402.
Financial Support
This research did not receive any financial support.
Authors’ Contributions
The author was responsible for all aspects of conducting the study.
Conflict of Interest
The author had no conflicts of interest.
Acknowledgments
The author sincerely thanks all participants for their valuable cooperation, as well as the administrators and staff of the healthcare centers in Urmia for their support throughout the study.
‎   References
Afshari, A., & Hashemi, Z. (2019). The relationship between religious exposure and psychological well-being with loneliness in the elderly. Aging Psychology, 5(1), 65-75. [Persian]‎
Afshari, A., & Rezaei, R. (2023). The Relationship between social support and coping styles with psychological well-being of the elderly: The Mediating role of self-esteem. Psychology of Aging, 8(4), 401-418. [Persian]‎
Aghah Harris, M., & Mousavi, A. (2012). Comparison of personality types in different levels of perceived stress, Journal of Behavioral Sciences, 4(11), 1-8. [Persian]
Anderson, D. M., Keith, J., Novak, P. D., & Elliot, M. A. (2002). Mosby's medical, nursing& allied health dictionary (6th ed.). St. Louis, MO: Mosby.
Ashoori, J., Alipour, A., & Arab Salari, Z. (2015). The Relationship between Defense Style, Religiosity, and Perceived Stress among Patients with Type I Diabetes. Journal of Diabetes, 3 (3), 51-62. Https://doi.org/20.1001. 1.23455020.1394.3.3.5.9 [Persian]
Azukaitis, K., Puteikis, K., Kinciniene, O., Mikucionyte, D., Mameniskiene, R., & Jankauskiene, A. (2024). Cognitive performance in children and adolescents with primary hypertension and the role of body mass. Frontiers in Pediatrics, 12, 1369690. Https://doi.org/10.3389/fped.2024.1369690
Badji, A., Pereira, J. B., Shams, S., Skoog, J., Marseglia, A., Poulakis, K., Badji, A., Pereira, J.B., Shams, S., Skoog, J., Marseglia, A., Poulakis, K., Rydén, L., Blennow, K., Zetterberg, H., Kern, S., Zettergren, A & Westman, E. (2022). Cerebrospinal fluid biomarkers, brain structural and cognitive performances between normotensive and hypertensive controlled, uncontrolled and untreated 70-year-old adults. Frontiers in Aging Neuroscience, 13, 777475. https://doi.org/10.3389 /fnagi. 2021.777475
Boyne, H., & Hamza, C. A. (2022). Depressive symptoms, perceived stress, self-compassion and no suicidal self-injury among emerging adults: an examination of the between and within-person associations over time. Emerging adulthood, 10(5), 1269-1285. Https://doi.org/10.1177/21676968211029768
Canavan, M., & O'Donnell, M. J. (2022). Hypertension and cognitive impairment: a review of mechanisms and key concepts. Frontiers in Neurology, 13, 821135. Https://doi.org/10.3389/fneur.2022.821135
Carmine, D., Aeschbacher, S., Coslovsky, M., Hennings, E., Paladini, R.E., Peter, R., Burger, M., Reichlin, T., Rodondi, N., Müller, A.S., Ammann, P., Conte, G., Auricchio, A., Moschovitis, G., Bardoczi, J.B., Stauber, A., De Perna, M.L., Zuern, C.S., Sinnecker, T., Badertscher, P., Sticherling, C., Bonati, L.H., Conen, D., Krisai, P., Osswald, S., & Kühne, M. (2024). Blood pressure, brain lesions and cognitive decline in patients with atrial fibrillation. Frontiers in Cardiovascular Medicine, 11, 1449506. Https://doi.org/10.3389/fcvm.2024.1449506
Clark, K. D. (2010). The Relationship of Perceived Stress and Self-Efficacy Among Correctional employees in Close-Security and Medium-Security-Level Institutions. Degree of Doctor of Phi-losophy, Psychology, Walden University           
Coelho-Júnior, H. J., Trichopoulou, A., & Panza, F. (2021). Cross-sectional and longitudinal associations between adherence to Mediterranean diet with physical performance and cognitive function in older adults: A systematic review and meta-analysis. Ageing research reviews, 70, 101395.  Https://doi.org/ 10. 1016/ j.arr.2021.101395.
Cohen, S., Kamarck, T., & Mermelstein, R. (1983). A Global measure of perceived stress. Journal of health and social behavior, 24(4),385-396. https://doi.org/10.2307/2136404
Doubova, S. V., Martinez-Vega, I. P., Aguirre-Hernandez, R., & Pérez-Cuevas, R. (2017). Association of hypertension-related distress with lack of self-care among hypertensive patients. Psychology, Health & Medicine, 22(1), 51-64.  Https://doi.org/ 10.1080/13548506.2016.1239830.
Elias, M. F., Goodell, A. L., & Dore, G. A. (2012). Hypertension and cognitive functioning: a perspective in historical context. Hypertension, 60(2), 260-268.  Https://doi.org/ 10.1161/HYPERTENSIONAHA. 111. 186429.
Emsaki, G., Molavi, H., Chitsaz, A., Movahed Abtahi, M., & Asgari, K. (2011). Psychometric properties of the Montreal Cognitive Assessment (MoCA) in Parkinson's disease patients in Isfahan. Journal of Isfahan Medical School, 29(158), 1606-1615. [Persian] ‎https://jims.mui.ac. ir/article_13553. html? lang =en
Evans-Polce, R. J., Schuler, M. S., Schulenberg, J. E., & Patrick, M. E. (2018). Gender-and age-varying associations of sensation seeking and substance use across young adulthood. Addictive behaviors, 84, 271-277. Https://doi.org/10.1016/j.addbeh.2018.05.003
Folkman, S., & Lazarus, R. S. (1986). Stress processes and depressive symptomatology. Journal of Abnormal Psychology, 84, 196-200.  Https://doi.org/ 10.1037//0021-843x.95.2.107.
Forte, G., & Casagrande, M. (2020). Effects of blood pressure on cognitive performance in aging: A systematic review. Brain sciences, 10(12), 919. Https://doi.org/10.3390/brainsci10120919
Goss, H. B. (2011). Wellness education: An integrated theoretical framework for fostering transformative learning (Doctoral dissertation, Queensland University of Technology).
Grande, G., Vanacore, N., Maggiore, L., Cucumo, V., Ghiretti, R., Galimberti, D., Scarpini, E., Mariani, C. & Clerici, F. (2014). Physical activity reduces the risk of dementia in mild cognitive impairment subjects: a cohort study. Journal of Alzheimer's disease, 39(4), 833-839.  Https://doi.org/10.3233/JAD-131808
Hansen, E. B., & Breivik, G. (2001). Sensation seeking as a predictor of positive and negative risk behaviour among adolescents. Personality and individual differences, 30(4), 627-640. Https://doi.org/10.1016/S0191-8869(00)00061-1
Harrington, F., Saxby, B. K., McKeith, I. G., Wesnes, K., & Ford, G. A. (2000). Cognitive performance in hypertensive and normotensive older subjects. Hypertension, 36(6), 1079-1082.  Https://doi.org/ 10.1161 /01. hyp.36.6.1079.
Hashemi, S. T., Alipour, A., & Zare, A. A. (2017). Fitting the self-integrable healthy lifestyle model in Iranian students. Research in Educational Systems, 11(36), 61-88. https://doi.org/10. 22034 /jiera. 2017.51086 [Persian]‎
Hestad, K., Engedal, K., Schirmer, H., & Strand, B. H. (2020). The Effect of blood pressure on cognitive performance. An 8-year follow-up of the Tromsø Study, comprising people aged 45–74 Years. Frontiers in psychology, 11, 607. https://doi.org/10.3389/fpsyg.2020.00607
Hettler, B. (1980). Wellness promotion on a university campus. Family & community health, 3(1), 77-95. Https://doi.org/ 10.1097/00003727-198005000-00008
Iadecola, C., Yaffe, K., Biller, J., Bratzke, L. C., Faraci, F. M., Gorelick, P. B., Gulati, M., Kamel, H., Knopman, D.S., Launer, L.J. & Zeki Al Hazzouri, A. (2016). Impact of hypertension on cognitive function: a scientific statement from the American Heart Association. Hypertension, 68(6), e67-e94.  Https://doi.org/10.1161/HYP.0000000000000053.
Ihle, A., Rimmele, U., Oris, M., Maurer, J., & Kliegel, M. (2020). The longitudinal relationship of perceived stress predicting subsequent decline in executive functioning in old age is attenuated in individuals with greater cognitive reserve. Gerontology, 66(1), 65-73. Https://doi.org/ 10.1159/000501293.
Jafari, A., & Dehghani Arani, Z. (2019). Predicting psychological well-being of women with hypertension based on perceived stress with the mediating role of cognitive emotion regulation. Psychiatry, 7(2), 40-47. https://sid.ir/paper/368064/fa [Persian]‎
Kakavand, A., & Demarcheli N. (2017). The Mediating role of perceived stress in the relationship between personality traits and hypertension in the elderly. Psychology of Gerontology, 2(4), 271-279.‎ https:// jap.razi.ac.ir/article_650.html [Persian]‎
Kassaeian, S. S., Danaei, N., Meshkat, S. A. M., Gharibi, F., Heidari Roochi, A., & Ebrahimi Tavani, M. (2024). Prevalence of Hypertension Complications and the Related Factors Among Older Adults in Semnan, Iran. Iranian Journal of Ageing, 19(2), 296-313. Https://doi.org/10.32598/sija.2023.3749.1 [Persian]‎
Littig, L., Sheth, K. N., Brickman, A. M., Mistry, E. A., & de Havenon, A. (2024). Blood Pressure and Cognitive Function in Older Adults. Clinics in Geriatric Medicine, 40(4), 597-613.  Https://doi.org/ 10.1016/ j.cger.2024.04.003.
Lynne-Landsman, S. D., Graber, J. A., Nichols, T. R., & Botvin, G. J. (2011). Is sensation seeking a stable trait or does it change over time? Journal of Youth and adolescence, 40, 48-58. Https://doi.org/10.1007/s10964-010-9529-2
Masoudnia, E. (2006). Perceived Stress Intensity and Strategies for Coping with It, Journal of Contemporary Psychology, 4, (2), 71-89 http://bjcp.ir/browse.php? aid= 289 &Sid= 1& slclan g= en . [Persian]
Mimura, C., & Griffiths, P. (2004). A Japanese version of the perceived stress scale: Translation and preliminary test. International journal of nursing studies, 41(4), 379-385. Https://doi.org/ 10.1016/ j.ijnurstu. 2003.10.009.
Mohammadi, M., Ghorbani, M., & Tabatabaei, F. (2014). Comparison of perceived stress with resilience in patients with type 2 diabetes and healthy individuals, Journal of Psychology and Behavioural Sciences, 7(1), 1-11. Https://doi.org/ 10.18502/ijdo.v14i4.11226 [Persian]
Moradi, A., & Mohammadi, M. (2020). Prediction of dark personality traits and self-destruction based on emotion regulation among adolescent females. Avicenna Journal of Neuro Psycho Physiology, 7(2), 109-115. 10.32592/ajnpp.2020.7.2.105
Mousavi, A. S., & Norouzi, L. (2022). Prediction of Self-Destructiveness based on Perceived Stress, Brain-behavioral Systems and Defense Styles. Journal of Modern Psychology, 2(3), 34-47.  Https://doi.org/org/10.22034/jmp.2023.388974.1053 [Persian]‎
Muela, H. C., Costa‐Hong, V. A., Yassuda, M. S., Moraes, N. C., Memória, C. M., Machado, M. F., Macedo, T.A., Shu, E.B., Massaro, A.R., Nitrini, R. & Bortolotto, L. A. (2017). Hypertension severity is associated with impaired cognitive performance. Journal of the American Heart Association, 6(1), e004579.  Https://doi.org/ 10.1161/JAHA.116.004579.
Myers, J. E., Luecht, R. M., & Sweeney, T. J. (2004). The Factor structure of wellness: Reexamining theoretical and empirical models underlying the wellness evaluation of lifestyle (WEL) and the five-factor WEL. Measurement and Evaluation in Counseling and Development, 36(4), 196–208. Https://doi.org/10.1080/07481756.2004.11909742
Myers, J. E., Sweeney, T. J., & Witmer, J. M. (2000). The Wheel of Wellness counseling for wellness: A Holistic model for treatment planning. Journal of Counseling & Development, 78(3), 251–266.  Https://doi.org/org/10.1002/j.1556-6676.2000.tb01906.x
Nasreddine, Z. S., Phillips, N. A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., Cummings, J.L. & Chertkow, H. (2005). The Montreal Cognitive Assessment, MoCA: A Brief screening tool for mild cognitive impairment. Journal of the American Geriatrics Society, 53(4), 695-699. Https://doi.org/ 10.1111/j.1532-5415.2005.53221.x.
Pace, U., Madonia, C., Passanisi, A., Iacolino, C., & Di Maggio, R. (2015). Is sensation seeking linked only to personality traits? The role of quality of attachment in the development of sensation seeking among Italian adolescents: A longitudinal perspective. Mediterranean Journal of Social Sciences, 6(2), S1. Https://doi.org/10.5901/mjss. 2015.v6n2s1p260
Pahlevanian, A. A., Najarian, R., Adabi, S., & Mirshoja, M. S. (2020). The Prevalence of fall and related factors in Iranian elderly: A Systematic review. Archives of Rehabilitation, 21(3), 286-303. http://rehabilitationj.uswr.ac.ir/article-1-2740-fa.html [Persian]‎
Peters, R. (2006). Ageing and the brain: This article is part of a series on ageing edited by Professor Chris Bulpitt. Postgraduate medical journal, 82(964), 84-88. Https://doi.org/10.1136/pgmj.2005.036665
Qiu, C., Winblad, B., & Fratiglioni, L. (2005). The age-dependent relation of blood pressure to cognitive function and dementia. The Lancet Neurology, 4(8), 487-499.  Https://doi.org/ 10.1016/S1474-4422(05)701411
Salehi, S., & Najarpour Ostadi, S. (2024). The Relationship Between Health-Promoting Lifestyle and Cognitive Functions in Older Adults with Hypertension: The Mediating Role of Perceived Stress. Aging Psychology, 10(2), 163-145. Https://doi.org/10.22126/JAP.2024.10328.1762 [Persian]‎
Saxby, B. K., Harrington, F., McKeith, I. G., Wesnes, K., & Ford, G. A. (2003). Effects of hypertension on attention, memory, and executive function in older adults. Health Psychology, 22(6), 587.  Https://doi.org/ 10. 1037/0278-6133.22.6.587.
Schneiderman, N., Ironson, G., & Siegel, S. D. (2005). Stress and health: psychological, behavioral, and biological determinants. Annu. Rev. Clin. Psychol., 1(1), 607-628.  Https://doi.org/10.1146/annurev.c linpsy.1 .102803.144141
Soltani, M., Foladvand, K., & Fathi Ashtiani, A. (2010). The Relationship between identity and sensation seeking with internet addiction. Journal of Behavioral Sciences, 4(3), 197-191. https:// www. behavsci .ir/article_67689.html [Persian]‎
Steinberg, L., Albert, D., Cauffman, E., Banich, M., Graham, S., & Woolard, J. (2008). Age differences in sensation seeking and impulsivity as indexed by behavior and self-report: evidence for a dual systems model. Developmental psychology, 44(6), 1764. Https://doi.org/10.1037/a0012955
Sun, X., Dong, C., Levin, B. E., Caunca, M., Zeki Al Hazzourie, A., DeRosa, J. T., ... & Sacco, R. L. (2021). Systolic blood pressure and cognition in the elderly: the northern manhattan study. Journal of Alzheimer's disease, 82(2), 689-699. Https://doi.org/10.3233/JAD-210252
Tadic, M., Cuspidi, C., & Hering, D. (2016). Hypertension and cognitive dysfunction in elderly: Blood pressure management for this global burden. BMC cardiovascular disorders, 16, 1-9.  Https://doi.org/ 10. 118 6 /s12872-016-0386-0
Turiano, N. A., Pitzer, L., Armour, C., Karlamangla, A., Ryff, C. D., & Mroczek, D. K. (2012). Personality trait level and change as predictors of health outcomes: Findings from a national study of Americans (MIDUS). The Journals of Gerontology: Series B: Psychological Sciences and Social Sciences, 67(1), 4–12. https://doi.org/10.1093/geronb/gbr072
Ungvari, Z., Toth, P., Tarantini, S., Prodan, C. I., Sorond, F., Merkely, B., & Csiszar, A. (2021). Hypertension-induced cognitive impairment: from pathophysiology to public health. Nature Reviews Nephrology, 17(10), 639-654. Https://doi.org/10.1038/s41581-021-00430-6
Vahedi Kojanagh, H. V., Afshari, A., Rezaei mollajigh, r., Eghbali, A., & Tayeri, M. (2020). The Prediction of the elderly’s life satisfaction based on health-promoting lifestyle. Aging, 6(3), 285-297. 10.22126/jap.2020.5626.1455 [Persian]‎
Vicario, A., Martinez, C. D., Baretto, D., Casale, A. D., & Nicolosi, L. (2005). Hypertension and cognitive decline: impact on executive function. The Journal of Clinical Hypertension, 7(10), 598-604. Https://doi.org/10. 1111/j.1524-6175.2005. 04498.x
Walker, K. A., Power, M. C., & Gottesman, R. F. (2017). Defining the relatio nship between hypertension, cognitive decline, and dementia: A Review. Current hypertension reports, 19, 1-16. Https://doi.org/ 10.1007/s11906-017-0724-3
Xian, G., Chai, Y., Gong, Y., He, W., Ma, C., Zhang, X., Xian, G., Chai, Y., Gong, Y., He, W., Ma, C., Zhang, X., Zhang, J. & Ma, Y. (2024). The relationship between healthy lifestyles and cognitive function in Chinese older adults: the mediating effect of depressive symptoms. BMC geriatrics, 24(1), 299. Https://doi.org/10.1186/s12877-024-04922-5
Yi, T., Su, Z., Wang, J., Gan, J., Wu, H., Shi, Z. ... & Ji, Y. (2024). Association between blood pressure and dementia in older adults: A Cross-sectional study from China. Frontiers in Aging Neuroscience, 16, 1466089. Https://doi.org/ 10.3389/fnagi.2024.1466089.
Zhu, M., Tian, X., Han, X., Ma, Y., Fa, W., Wang, N., Liu, R., Dong, Y., Ren, Y., Liu, C., Tian, N., Zhang, H., Song, L., Tang, S., Cong, L., Wang, Y., Hou, T., Qiu, C., & Du, Y. (2024). Synergistic associations of CD33 variants and hypertension with brain and cognitive aging among dementia‐free older adults: A Population‐based study. Alzheimer's & Dementia. 20 (10), 7193-7204. Https://doi.org/ 10.1002/alz.14209
Zuckerman, M., Eysenck, S. B., & Eysenck, H. J. (1978). Sensation seeking in England and America: Cross-cultural, age, and sex comparisons. Journal of consulting and clinical psychology, 46(1), 139. Https://doi.org/10.1037//0022-006x.46.1.139
 

Keywords

Main Subjects


References
Afshari, A., & Hashemi, Z. (2019). The relationship between religious exposure and psychological well-being with loneliness in the elderly. Aging Psychology, 5(1), 65-75. [Persian]‎
Afshari, A., & Rezaei, R. (2023). The Relationship between social support and coping styles with psychological well-being of the elderly: The Mediating role of self-esteem. Psychology of Aging, 8(4), 401-418. [Persian]‎
Aghah Harris, M., & Mousavi, A. (2012). Comparison of personality types in different levels of perceived stress, Journal of Behavioral Sciences, 4(11), 1-8. [Persian]
Anderson, D. M., Keith, J., Novak, P. D., & Elliot, M. A. (2002). Mosby's medical, nursing& allied health dictionary (6th ed.). St. Louis, MO: Mosby.
Ashoori, J., Alipour, A., & Arab Salari, Z. (2015). The Relationship between Defense Style, Religiosity, and Perceived Stress among Patients with Type I Diabetes. Journal of Diabetes, 3 (3), 51-62. Https://doi.org/20.1001. 1.23455020.1394.3.3.5.9 [Persian]
Azukaitis, K., Puteikis, K., Kinciniene, O., Mikucionyte, D., Mameniskiene, R., & Jankauskiene, A. (2024). Cognitive performance in children and adolescents with primary hypertension and the role of body mass. Frontiers in Pediatrics, 12, 1369690. Https://doi.org/10.3389/fped.2024.1369690
Badji, A., Pereira, J. B., Shams, S., Skoog, J., Marseglia, A., Poulakis, K., Badji, A., Pereira, J.B., Shams, S., Skoog, J., Marseglia, A., Poulakis, K., Rydén, L., Blennow, K., Zetterberg, H., Kern, S., Zettergren, A & Westman, E. (2022). Cerebrospinal fluid biomarkers, brain structural and cognitive performances between normotensive and hypertensive controlled, uncontrolled and untreated 70-year-old adults. Frontiers in Aging Neuroscience, 13, 777475. https://doi.org/10.3389 /fnagi. 2021.777475
Boyne, H., & Hamza, C. A. (2022). Depressive symptoms, perceived stress, self-compassion and no suicidal self-injury among emerging adults: an examination of the between and within-person associations over time. Emerging adulthood, 10(5), 1269-1285. Https://doi.org/10.1177/21676968211029768
Canavan, M., & O'Donnell, M. J. (2022). Hypertension and cognitive impairment: a review of mechanisms and key concepts. Frontiers in Neurology, 13, 821135. Https://doi.org/10.3389/fneur.2022.821135
Carmine, D., Aeschbacher, S., Coslovsky, M., Hennings, E., Paladini, R.E., Peter, R., Burger, M., Reichlin, T., Rodondi, N., Müller, A.S., Ammann, P., Conte, G., Auricchio, A., Moschovitis, G., Bardoczi, J.B., Stauber, A., De Perna, M.L., Zuern, C.S., Sinnecker, T., Badertscher, P., Sticherling, C., Bonati, L.H., Conen, D., Krisai, P., Osswald, S., & Kühne, M. (2024). Blood pressure, brain lesions and cognitive decline in patients with atrial fibrillation. Frontiers in Cardiovascular Medicine, 11, 1449506. Https://doi.org/10.3389/fcvm.2024.1449506
Clark, K. D. (2010). The Relationship of Perceived Stress and Self-Efficacy Among Correctional employees in Close-Security and Medium-Security-Level Institutions. Degree of Doctor of Phi-losophy, Psychology, Walden University           
Coelho-Júnior, H. J., Trichopoulou, A., & Panza, F. (2021). Cross-sectional and longitudinal associations between adherence to Mediterranean diet with physical performance and cognitive function in older adults: A systematic review and meta-analysis. Ageing research reviews, 70, 101395.  Https://doi.org/ 10. 1016/ j.arr.2021.101395.
Cohen, S., Kamarck, T., & Mermelstein, R. (1983). A Global measure of perceived stress. Journal of health and social behavior, 24(4),385-396. https://doi.org/10.2307/2136404
Doubova, S. V., Martinez-Vega, I. P., Aguirre-Hernandez, R., & Pérez-Cuevas, R. (2017). Association of hypertension-related distress with lack of self-care among hypertensive patients. Psychology, Health & Medicine, 22(1), 51-64.  Https://doi.org/ 10.1080/13548506.2016.1239830.
Elias, M. F., Goodell, A. L., & Dore, G. A. (2012). Hypertension and cognitive functioning: a perspective in historical context. Hypertension, 60(2), 260-268.  Https://doi.org/ 10.1161/HYPERTENSIONAHA. 111. 186429.
Emsaki, G., Molavi, H., Chitsaz, A., Movahed Abtahi, M., & Asgari, K. (2011). Psychometric properties of the Montreal Cognitive Assessment (MoCA) in Parkinson's disease patients in Isfahan. Journal of Isfahan Medical School, 29(158), 1606-1615. [Persian] ‎https://jims.mui.ac. ir/article_13553. html? lang =en
Evans-Polce, R. J., Schuler, M. S., Schulenberg, J. E., & Patrick, M. E. (2018). Gender-and age-varying associations of sensation seeking and substance use across young adulthood. Addictive behaviors, 84, 271-277. Https://doi.org/10.1016/j.addbeh.2018.05.003
Folkman, S., & Lazarus, R. S. (1986). Stress processes and depressive symptomatology. Journal of Abnormal Psychology, 84, 196-200.  Https://doi.org/ 10.1037//0021-843x.95.2.107.
Forte, G., & Casagrande, M. (2020). Effects of blood pressure on cognitive performance in aging: A systematic review. Brain sciences, 10(12), 919. Https://doi.org/10.3390/brainsci10120919
Goss, H. B. (2011). Wellness education: An integrated theoretical framework for fostering transformative learning (Doctoral dissertation, Queensland University of Technology).
Grande, G., Vanacore, N., Maggiore, L., Cucumo, V., Ghiretti, R., Galimberti, D., Scarpini, E., Mariani, C. & Clerici, F. (2014). Physical activity reduces the risk of dementia in mild cognitive impairment subjects: a cohort study. Journal of Alzheimer's disease, 39(4), 833-839.  Https://doi.org/10.3233/JAD-131808
Hansen, E. B., & Breivik, G. (2001). Sensation seeking as a predictor of positive and negative risk behaviour among adolescents. Personality and individual differences, 30(4), 627-640. Https://doi.org/10.1016/S0191-8869(00)00061-1
Harrington, F., Saxby, B. K., McKeith, I. G., Wesnes, K., & Ford, G. A. (2000). Cognitive performance in hypertensive and normotensive older subjects. Hypertension, 36(6), 1079-1082.  Https://doi.org/ 10.1161 /01. hyp.36.6.1079.
Hashemi, S. T., Alipour, A., & Zare, A. A. (2017). Fitting the self-integrable healthy lifestyle model in Iranian students. Research in Educational Systems, 11(36), 61-88. https://doi.org/10. 22034 /jiera. 2017.51086 [Persian]‎
Hestad, K., Engedal, K., Schirmer, H., & Strand, B. H. (2020). The Effect of blood pressure on cognitive performance. An 8-year follow-up of the Tromsø Study, comprising people aged 45–74 Years. Frontiers in psychology, 11, 607. https://doi.org/10.3389/fpsyg.2020.00607
Hettler, B. (1980). Wellness promotion on a university campus. Family & community health, 3(1), 77-95. Https://doi.org/ 10.1097/00003727-198005000-00008
Iadecola, C., Yaffe, K., Biller, J., Bratzke, L. C., Faraci, F. M., Gorelick, P. B., Gulati, M., Kamel, H., Knopman, D.S., Launer, L.J. & Zeki Al Hazzouri, A. (2016). Impact of hypertension on cognitive function: a scientific statement from the American Heart Association. Hypertension, 68(6), e67-e94.  Https://doi.org/10.1161/HYP.0000000000000053.
Ihle, A., Rimmele, U., Oris, M., Maurer, J., & Kliegel, M. (2020). The longitudinal relationship of perceived stress predicting subsequent decline in executive functioning in old age is attenuated in individuals with greater cognitive reserve. Gerontology, 66(1), 65-73. Https://doi.org/ 10.1159/000501293.
Jafari, A., & Dehghani Arani, Z. (2019). Predicting psychological well-being of women with hypertension based on perceived stress with the mediating role of cognitive emotion regulation. Psychiatry, 7(2), 40-47. https://sid.ir/paper/368064/fa [Persian]‎
Kakavand, A., & Demarcheli N. (2017). The Mediating role of perceived stress in the relationship between personality traits and hypertension in the elderly. Psychology of Gerontology, 2(4), 271-279.‎ https:// jap.razi.ac.ir/article_650.html [Persian]‎
Kassaeian, S. S., Danaei, N., Meshkat, S. A. M., Gharibi, F., Heidari Roochi, A., & Ebrahimi Tavani, M. (2024). Prevalence of Hypertension Complications and the Related Factors Among Older Adults in Semnan, Iran. Iranian Journal of Ageing, 19(2), 296-313. Https://doi.org/10.32598/sija.2023.3749.1 [Persian]‎
Littig, L., Sheth, K. N., Brickman, A. M., Mistry, E. A., & de Havenon, A. (2024). Blood Pressure and Cognitive Function in Older Adults. Clinics in Geriatric Medicine, 40(4), 597-613.  Https://doi.org/ 10.1016/ j.cger.2024.04.003.
Lynne-Landsman, S. D., Graber, J. A., Nichols, T. R., & Botvin, G. J. (2011). Is sensation seeking a stable trait or does it change over time? Journal of Youth and adolescence, 40, 48-58. Https://doi.org/10.1007/s10964-010-9529-2
Masoudnia, E. (2006). Perceived Stress Intensity and Strategies for Coping with It, Journal of Contemporary Psychology, 4, (2), 71-89 http://bjcp.ir/browse.php? aid= 289 &Sid= 1& slclan g= en . [Persian]
Mimura, C., & Griffiths, P. (2004). A Japanese version of the perceived stress scale: Translation and preliminary test. International journal of nursing studies, 41(4), 379-385. Https://doi.org/ 10.1016/ j.ijnurstu. 2003.10.009.
Mohammadi, M., Ghorbani, M., & Tabatabaei, F. (2014). Comparison of perceived stress with resilience in patients with type 2 diabetes and healthy individuals, Journal of Psychology and Behavioural Sciences, 7(1), 1-11. Https://doi.org/ 10.18502/ijdo.v14i4.11226 [Persian]
Moradi, A., & Mohammadi, M. (2020). Prediction of dark personality traits and self-destruction based on emotion regulation among adolescent females. Avicenna Journal of Neuro Psycho Physiology, 7(2), 109-115. 10.32592/ajnpp.2020.7.2.105
Mousavi, A. S., & Norouzi, L. (2022). Prediction of Self-Destructiveness based on Perceived Stress, Brain-behavioral Systems and Defense Styles. Journal of Modern Psychology, 2(3), 34-47.  Https://doi.org/org/10.22034/jmp.2023.388974.1053 [Persian]‎
Muela, H. C., Costa‐Hong, V. A., Yassuda, M. S., Moraes, N. C., Memória, C. M., Machado, M. F., Macedo, T.A., Shu, E.B., Massaro, A.R., Nitrini, R. & Bortolotto, L. A. (2017). Hypertension severity is associated with impaired cognitive performance. Journal of the American Heart Association, 6(1), e004579.  Https://doi.org/ 10.1161/JAHA.116.004579.
Myers, J. E., Luecht, R. M., & Sweeney, T. J. (2004). The Factor structure of wellness: Reexamining theoretical and empirical models underlying the wellness evaluation of lifestyle (WEL) and the five-factor WEL. Measurement and Evaluation in Counseling and Development, 36(4), 196–208. Https://doi.org/10.1080/07481756.2004.11909742
Myers, J. E., Sweeney, T. J., & Witmer, J. M. (2000). The Wheel of Wellness counseling for wellness: A Holistic model for treatment planning. Journal of Counseling & Development, 78(3), 251–266.  Https://doi.org/org/10.1002/j.1556-6676.2000.tb01906.x
Nasreddine, Z. S., Phillips, N. A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., Cummings, J.L. & Chertkow, H. (2005). The Montreal Cognitive Assessment, MoCA: A Brief screening tool for mild cognitive impairment. Journal of the American Geriatrics Society, 53(4), 695-699. Https://doi.org/ 10.1111/j.1532-5415.2005.53221.x.
Pace, U., Madonia, C., Passanisi, A., Iacolino, C., & Di Maggio, R. (2015). Is sensation seeking linked only to personality traits? The role of quality of attachment in the development of sensation seeking among Italian adolescents: A longitudinal perspective. Mediterranean Journal of Social Sciences, 6(2), S1. Https://doi.org/10.5901/mjss. 2015.v6n2s1p260
Pahlevanian, A. A., Najarian, R., Adabi, S., & Mirshoja, M. S. (2020). The Prevalence of fall and related factors in Iranian elderly: A Systematic review. Archives of Rehabilitation, 21(3), 286-303. http://rehabilitationj.uswr.ac.ir/article-1-2740-fa.html [Persian]‎
Peters, R. (2006). Ageing and the brain: This article is part of a series on ageing edited by Professor Chris Bulpitt. Postgraduate medical journal, 82(964), 84-88. Https://doi.org/10.1136/pgmj.2005.036665
Qiu, C., Winblad, B., & Fratiglioni, L. (2005). The age-dependent relation of blood pressure to cognitive function and dementia. The Lancet Neurology, 4(8), 487-499.  Https://doi.org/ 10.1016/S1474-4422(05)701411
Salehi, S., & Najarpour Ostadi, S. (2024). The Relationship Between Health-Promoting Lifestyle and Cognitive Functions in Older Adults with Hypertension: The Mediating Role of Perceived Stress. Aging Psychology, 10(2), 163-145. Https://doi.org/10.22126/JAP.2024.10328.1762 [Persian]‎
Saxby, B. K., Harrington, F., McKeith, I. G., Wesnes, K., & Ford, G. A. (2003). Effects of hypertension on attention, memory, and executive function in older adults. Health Psychology, 22(6), 587.  Https://doi.org/ 10. 1037/0278-6133.22.6.587.
Schneiderman, N., Ironson, G., & Siegel, S. D. (2005). Stress and health: psychological, behavioral, and biological determinants. Annu. Rev. Clin. Psychol., 1(1), 607-628.  Https://doi.org/10.1146/annurev.c linpsy.1 .102803.144141
Soltani, M., Foladvand, K., & Fathi Ashtiani, A. (2010). The Relationship between identity and sensation seeking with internet addiction. Journal of Behavioral Sciences, 4(3), 197-191. https:// www. behavsci .ir/article_67689.html [Persian]‎
Steinberg, L., Albert, D., Cauffman, E., Banich, M., Graham, S., & Woolard, J. (2008). Age differences in sensation seeking and impulsivity as indexed by behavior and self-report: evidence for a dual systems model. Developmental psychology, 44(6), 1764. Https://doi.org/10.1037/a0012955
Sun, X., Dong, C., Levin, B. E., Caunca, M., Zeki Al Hazzourie, A., DeRosa, J. T., ... & Sacco, R. L. (2021). Systolic blood pressure and cognition in the elderly: the northern manhattan study. Journal of Alzheimer's disease, 82(2), 689-699. Https://doi.org/10.3233/JAD-210252
Tadic, M., Cuspidi, C., & Hering, D. (2016). Hypertension and cognitive dysfunction in elderly: Blood pressure management for this global burden. BMC cardiovascular disorders, 16, 1-9.  Https://doi.org/ 10. 118 6 /s12872-016-0386-0
Turiano, N. A., Pitzer, L., Armour, C., Karlamangla, A., Ryff, C. D., & Mroczek, D. K. (2012). Personality trait level and change as predictors of health outcomes: Findings from a national study of Americans (MIDUS). The Journals of Gerontology: Series B: Psychological Sciences and Social Sciences, 67(1), 4–12. https://doi.org/10.1093/geronb/gbr072
Ungvari, Z., Toth, P., Tarantini, S., Prodan, C. I., Sorond, F., Merkely, B., & Csiszar, A. (2021). Hypertension-induced cognitive impairment: from pathophysiology to public health. Nature Reviews Nephrology, 17(10), 639-654. Https://doi.org/10.1038/s41581-021-00430-6
Vahedi Kojanagh, H. V., Afshari, A., Rezaei mollajigh, r., Eghbali, A., & Tayeri, M. (2020). The Prediction of the elderly’s life satisfaction based on health-promoting lifestyle. Aging, 6(3), 285-297. 10.22126/jap.2020.5626.1455 [Persian]‎
Vicario, A., Martinez, C. D., Baretto, D., Casale, A. D., & Nicolosi, L. (2005). Hypertension and cognitive decline: impact on executive function. The Journal of Clinical Hypertension, 7(10), 598-604. Https://doi.org/10. 1111/j.1524-6175.2005. 04498.x
Walker, K. A., Power, M. C., & Gottesman, R. F. (2017). Defining the relatio nship between hypertension, cognitive decline, and dementia: A Review. Current hypertension reports, 19, 1-16. Https://doi.org/ 10.1007/s11906-017-0724-3
Xian, G., Chai, Y., Gong, Y., He, W., Ma, C., Zhang, X., Xian, G., Chai, Y., Gong, Y., He, W., Ma, C., Zhang, X., Zhang, J. & Ma, Y. (2024). The relationship between healthy lifestyles and cognitive function in Chinese older adults: the mediating effect of depressive symptoms. BMC geriatrics, 24(1), 299. Https://doi.org/10.1186/s12877-024-04922-5
Yi, T., Su, Z., Wang, J., Gan, J., Wu, H., Shi, Z. ... & Ji, Y. (2024). Association between blood pressure and dementia in older adults: A Cross-sectional study from China. Frontiers in Aging Neuroscience, 16, 1466089. Https://doi.org/ 10.3389/fnagi.2024.1466089.
Zhu, M., Tian, X., Han, X., Ma, Y., Fa, W., Wang, N., Liu, R., Dong, Y., Ren, Y., Liu, C., Tian, N., Zhang, H., Song, L., Tang, S., Cong, L., Wang, Y., Hou, T., Qiu, C., & Du, Y. (2024). Synergistic associations of CD33 variants and hypertension with brain and cognitive aging among dementia‐free older adults: A Population‐based study. Alzheimer's & Dementia. 20 (10), 7193-7204. Https://doi.org/ 10.1002/alz.14209
Zuckerman, M., Eysenck, S. B., & Eysenck, H. J. (1978). Sensation seeking in England and America: Cross-cultural, age, and sex comparisons. Journal of consulting and clinical psychology, 46(1), 139. Https://doi.org/10.1037//0022-006x.46.1.139